Top Senior IT Jobs in San Francisco Bay Area, CA

Own day-to-day IT operations, service management, endpoint security, identity and access administration, cloud infrastructure support, vendor and MSP oversight, business-unit technology integrations, and SOC 2 or other audit readiness. The role manages Microsoft 365, Google Workspace, AWS, Azure, endpoint tools, security platforms, device compliance, operational documentation, procurement, and technical evidence across multiple business units.

Owns IT infrastructure, endpoint management, identity and access, security, compliance, vendor relationships, and employee support across corporate and clinical teams. The role designs scalable systems, resolves hardware and software issues, manages provisioning and deprovisioning, develops IT policies and documentation, supports HIPAA and SOC 2 compliance, and maintains disaster recovery and cybersecurity response practices. Periodic travel to regional offices is required.

Own end-to-end IT for a multi-site startup, including employee support, onboarding and offboarding, device management, identity and access, office infrastructure, vendors, AI tooling governance, security operations, and CMMC/NIST compliance. Develop security policies, incident response playbooks, audit readiness, scalable IT processes, budgets, and strategic roadmaps while advising leadership and supporting defense-related requirements.

Build and lead DeployCo’s internal IT function from the ground up. Design and administer identity, endpoint, SaaS, networking, support, asset, and collaboration systems; automate employee lifecycle workflows; partner with Security and Engineering on controls and technical operations; manage vendors, budget, procurement, and hardware logistics; and hire and coach a hands-on IT team.

Provides high-touch, end-to-end IT support for Airbnb executives and Executive Business Partners. Troubleshoots endpoints, mobile devices, identity, connectivity, collaboration tools, AV, and workplace technology; coordinates complex issues across technical teams; prepares technology for leadership meetings, travel, and events; leads improvements, standards, documentation, mentoring, and executive support strategy. Requires after-hours coverage and occasional onsite, travel, event, or residential support.

Provide Tier 1 and Tier 2 IT support, executive assistance, onboarding, SaaS administration, and IT systems management. Configure MDM, SSO, ticketing, and identity systems; automate provisioning and offboarding; support IT security initiatives; manage SaaS spend; and coordinate technology requirements for new office buildouts, including networking, audiovisual, and security equipment.

Leads end-user technology services, supporting workstations, mobile devices, video conferencing, voice systems, and collaboration tools. Troubleshoots complex technical issues, manages incidents and root-cause analysis, automates operational tasks with scripting, creates documentation and training, coordinates vendors and technology projects, and supports hardware lifecycle activities. Provides rotational 24x7 on-call coverage and domestic and international deployment support.

Leads OLIPOP’s IT strategy, operations, security, compliance, vendor management, and cross-functional technology projects. Oversees cloud systems, networking, endpoint management, SaaS lifecycle, helpdesk operations, onboarding and offboarding, access governance, and user support. Manages IT policies, budgets, audits, security tools, incident response, and vendor relationships while balancing strategic planning with hands-on technical execution.

Own employee IT support, device lifecycle management, identity and SaaS administration, office infrastructure, onboarding, and scalable IT processes. The role supports macOS and Windows environments, MDM, SSO, Google Workspace, Slack, networking, AV, conference rooms, access controls, compliance, and asset management. It is a hands-on, on-site position requiring strong troubleshooting, documentation, communication, and customer-service skills.

Leads enterprise IT strategy, operations, cybersecurity, compliance, infrastructure, business applications, and end-user services. Manages internal IT leaders, MSPs, and strategic technology partners while improving service delivery, employee technology experience, business continuity, and disaster recovery. Partners cross-functionally to support clinical and corporate platforms, strengthen security, and enable responsible AI and automation. Owns IT investment planning, vendor performance, operational metrics, and technology roadmaps in a regulated biopharmaceutical environment.

Own IT operations for a 60-person hybrid company, including end-user support, Mac fleet and device management, identity and access administration, SaaS and vendor management, office networking and AV, onboarding and offboarding, security configurations, and process documentation. Administer AI tools, support adoption and training, evaluate technology, manage licenses and costs, and establish scalable IT workflows as the company grows.

Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.

Supports laboratory computing environments, scientific instruments, laboratory software, connected workstations, and IT infrastructure in a regulated biotech or pharmaceutical setting. Responsibilities include deployments, upgrades, troubleshooting, network connectivity, security patching, compliance, CMDB and inventory maintenance, vendor coordination, laboratory expansions, technical documentation, and IT project leadership.

Build and run a white-glove executive support function: own intake, SLAs, runbooks, and escalations for executives, ABPs, and board. Provide AV support for board meetings and exec rooms, handle urgent tech incidents, work shared ticket queue, participate in on-call rotation, maintain San Francisco on-site presence, and document processes and KB content.

Provide end-user IT support across hardware, software, networking, and accounts (primarily macOS) via tickets, Slack, and in-person; maintain documentation and runbooks; manage device enrollment, MDM, identity and access workflows; participate in on-call rotation; automate repetitive tasks with scripting; improve onboarding and operational processes.

Build and lead a centralized IT function across a holding company and portfolio. Run acquisition IT workstreams and create a Day 1-100 integration playbook. Select and operate identity and access systems, build joiner/mover/leaver processes, maintain living inventory of tools/accounts/licenses, manage MSP relationships and vendor contracts, and connect back-end systems to the cross-portfolio data platform while engaging business stakeholders.

Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.

Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.